10 Best Wireless Mouse For Large Hands 2022 – Reviews & Guide

List of Best Wireless Mouse For Large Hands

Larger mice can be an excellent choice for those with larger hands. A larger mouse will give your fingers more space and a less cramped feel, however finding the right sized mouse is not as easy as it seems. You will want to make sure that you are getting a large mouse that can still fit comfortably in your hand without any pressure on your hand or fingers to push or squeeze the mouse.

It is important that you find a mouse that can not only fit well in your hand but also one that gives the correct amount of support to the wrist. For example, if you have a large hand but dont have a lot of wrist support, it could end up hurting your wrist if using a small mouse.

Read Also: 10 Best Mouse For Sim 4 2022 – Reviews & Guide

The Logitech MX Master is the best wireless mouse for large hands, thanks to its unmatched capability for fine-tuning controls and long battery life. By improving upon some of the biggest strengths of the previous MX models, Logitech has delivered what is by far the most impressive feature set we’ve ever seen in a mouse. You can learn more about choosing the best mouse to suit your needs, but if you’re looking for a great all-in-one solution with lots of extra features that really take things to the next level, the MX Master is it.

1. iClever Ergonomic Mouse


  • Connectivity Technology :Wireless, USB
  • Brand : IClever
  • Movement Detection Technology : Optical
  • Number of Buttons : 6
  • Item Dimensions LxWxH : 5.43 x 2.95 x 2.68 inches

iClever Ergonomic Mouse – Wireless Vertical Mouse 6 Buttons with Adjustable DPI Comfortable 2.4G Optical Vertical Ergonomic Mouse for Mac, PC, Desktop, Laptop is a unique ergonomic mouse that would never cause RSI from constant usage, as it’s carefully engineered to fit your hand and natural movements.

Experience the 2.4G Vertical Ergonomic Mouse from iClever, a wireless peripheral on your desktop or laptop computer that adapts ergonomically to your hand for fluid movement and comfort, minimizing wrist strain and fatigue even after long hours of use.

Equipped with 3 DPI settings, this 6-button USB optical mouse moves smoothly for precision operation, letting you enjoy sweeping page scroll with least exertion. Effectively reduce the stress between shoulder and wrist joints and recommendable for long-term mouse application.

2. AUTLEY Vertical Wireless Mouse


  • Connectivity Technology : Wireless
  • Recommended Uses For Product : Office
  • Brand : AUTLEY
  • Compatible Devices : Laptop, Personal Computer
  • Movement Detection Technology : Optical

Our Vertical Wireless Mouse improves your productivity by reducing repetitive stress on hand and wrist. Its Ergonomic Design and Large Size let you work more comfortably. Silent Click ensures a quiet working environment. It’s compatible with Windows®8 / 7/10 / Vista/XP/2000, Mac, Linux (NOTE: The side forward/backward button is not recognized on Mac).

You can connect this vertical ergonomic mouse to your computer with the USB receiver (included), or you can use it as a wireless mouse with its built-in AA battery. It has 800/1200/1600 DPI (Slow to fast) adjustable DPI via DPI button. We’ve also included 3 x replacement feet for soft/hard surface mouse pad.

3. Hippus L2UB-LC Wireless Light Click HandShoe Mouse


  • Connectivity Technology : Wireless
  • Brand : Hippus
  • Color : Black
  • Number of Buttons : 2

Whether you are simply looking for a new mouse, or upgrading from an outdated one, the Hippus L2UB-LC Wireless Light Click HandShoe Mouse is the perfect choice. With its wireless capabilities, ergonomic design and simple yet comfortable button placement, the L2UB-LC will be your go-to device whenever you need to locate or move information. Offering a wireless range of up to 30 feet, having your mouse within reach has never been easier.

The Hippus L2UB-LC Wireless Light Click HandShoe Mouse is a 2 button mouse that works either with a USB receiver for use with a computer or with an RF wireless dongle for use with a laptop. It has been ergonomically designed to fit the hand, and is linked to popular programs used on many programs including Microsoft Word, Excel, PowerPoint and Outlook. The Hippus L2UB-LC Wireless Light Click HandShoe Mouse features include:

4. Evoluent VMDL VerticalMouse D Large Right-Hand Ergonomic Mouse 


  • Connectivity Technology : USB
  • Brand : Evoluent
  • Compatible Devices :PC, Mac
  • Movement Detection Technology :Optical
  • Color : Black, Silver, Grey

The Evoluent VMDL VerticalMouse D Large Right-Hand Ergonomic Mouse is the favorite of professionals in field such as graphic design, musical composition/sound editing, engineering and CAD, as well as home users who spend long hours at their PC. The Evoluent VMDL provides comfort to right-handed users through its effortless positioning which frees up your hand and wrist.

Plus, you can program the VerticalMouse’s buttons with the Evoluent Mouse Manager software which allows you to configure how the buttons work within different programs. The Evoluent VMDL VerticalMouse D Large is an ergonomic right-handed mouse that lets you control your mouse through a natural pendulum-like movement of your arm.

The shape of the VMDL allows it to fit to your hand perfectly, while providing an upright comfortable working position. The patented shape encourages neutral hand and wrist positions, reducing muscle strain and discomfort and allowing users to work longer.

5. Lekvey Left Hand Mouse


  • Connectivity Technology : Wireless, USB
  • Recommended Uses For Product : Gaming
  • Brand : Lekvey
  • Compatible Devices : Laptop, Personal Computer
  • Special Feature : Left Handed Ergonomic Wireless Mouse, Quiet Click

Lekvey 2.4Ghz Wireless Vertical ERGONOMIC LEFT HAND Mouse is specifically designed to be used by left-handers. It’s a great solution for both PC/Mac users with Repetitive Strain Injuries RSI as well as healthy users who just want to improve their comfort and workflow. Lekvey vertical mouse features a nice big soft rubber wheel, which provides you great feedback without much clicking.

This mouse incorporates a high precision optical tracking engine and advanced human engineering, making it ultra responsive to the slightest movements. It allows you to work faster and safer on your computer, and provides increased comfort especially to people suffering from wrist pain. Using Lekvey Vertical Mouse will significantly decrease the risks of wrist pains while improving your ability to multi-task  on your computer.

6. SteelSeries Sensei 310 Gaming Mouse 


  • Connectivity Technology : USB
  • Brand : SteelSeries
  • Series : 62432
  • Movement Detection Technology : Optical
  • Color : Black

The SteelSeries Sensei 310 gaming mouse combines professional-grade software with precision hardware. Tracking up to 200 inches per second and 12,000 CPI, the Sensei 310 uses a TrueMove3 12,000 CPI optical sensor and SteelSeries Engine 3 software for exact 1-to-1 tracking capability for a high amount of accuracy.

This is a great choice for both competitive esports players as well as casual gamers looking for their next step up from a basic USB laser mouse. Featuring an ambidextrous design, the Sensei 310 will fit comfortably in the claw or palm grip style of any user. Prism RGB illumination gives you two zones for custom color settings (nine colors total) that can be saved to the on-board memory so they are always ready when you turn on your PC or Mac.

The SteelSeries Sensei 310 Gaming Mouse is the updated version of the Sensei. The design combines ergonomics, comfort and performance with a 12,000 CPI sensor and esports ambidextrous shape that suits both palm and claw grip styles. New features include an all new Prism RGB illumination for customizable light effects which can be saved directly to the mouse, plus multi-color lighting zones for over 100 color combinations.

7. Logitech Trackman Marble Trackball Mouse


  • Connectivity Technology : PS/2, USB
  • Brand : Logitech
  • Model Name : 910-000806
  • Movement Detection Technology : Optical
  • Color : Dark Silver

The Logitech Trackman Marble Trackball Mouse features sculpted shape that supports your right or left hand and stays in one place – move the cursor without moving your arm. This convenient ambidexterous design gives you highly comfortable, responsive control. It provides a natural feel when navigating whether on your PC or Mac® computer.

The Logitech Trackman Marble Mouse features four programmable buttons that let you customize it the way you want. And it’s great for either hand thanks to its sculpted ambidexterous design that stays in one place—move the cursor without moving your arm. There is also a trackball on the underside that can be used for scrolling through documents, zooming in and out of Web pages, or bringing up lists of items. (Logitech software is required for programming trackball functions).

The Logitech Trackman Marble trackball mouse delivers more than comfort for your hand, it gives you total control. The sculpted ambidexterous shape supports right- or lefthanded use and stays in one place as you move the cursor – without moving your arm. The trackball gives you smooth, precise tracking and navigation, no matter where or how far you move the pointer on your screen.

Large, easy-to-reach Back/Forward buttons make browsing Web sites or moving between documents a snap. And four programmable buttons give you precise control over what those buttons do and when they do it.

8. TECKNET Pro 2.4G Ergonomic Wireless Optical Mouse


  • Connectivity Technology : Wireless, Wi-Fi, USB
  • Brand : TECKNET
  • Special Feature : Comfortable Design, TruWave Precision
  • Movement Detection Technology : Optical
  • Color : Red

TECKNET Pro 2.4G Ergonomic Wireless Optical Mouse with USB Nano Receiver for Laptop,PC,Computer,Chromebook,Notebook,6 Buttons,24 Months Battery Life, 2600 DPI, 5 Adjustment Levels, Plug and Play – Comes with a tiny USB Nano receiver(stored within the back of the mouse) , just plug it into your PC and then forget it.

6 Buttons – Easily go back and forth between links or pictures on webpages using left/ right buttons. 5 Adjustable DPI Level – choose your own cursor speed! 24 Months Battery Life – according to a AAA NI-MH battery capacity test; long lasting performance backed by high quality cells. 2.4G Technology – provides super fast responsiveness. 26-month battery life – compared with an ordinary mouse whose product cycle is 12 months (1 AA alkaline battery = approx 5000 times).

The TeckNet Pro 2.4G Ergonomic Wireless Optical Mouse delivers reliable 2.4GHz wireless connectivity with a plug-and-play Nano USB Receiver. With a tilt wheel and contoured design, you can work in comfort for extended periods of time without straining your hand and wrist. Enjoy precision cursor control over many types of surfaces using the 5 adjustable DPI levels to choose from.

Often imitated but never duplicated, this ergonomic mouse features 24 months battery life, dual side switch mode, and true 2400DPI optical sensor with TeckNet Tru-Wave technology that ensure that you get the best performance with every use.

9. J-Tech Digital Ergonomic Mouse 


  • Connectivity Technology : 2.4G Wireless
  • Brand : J-Tech Digital
  • Movement Detection Technology : Optical
  • Color : Black, RGB LED Light
  • Style : Right Hand Black RGB LED

The J-Tech Digital V638’s comfortable, ergonomic “handshake” design greatly reduces arm/wrist/hand strain. Back/forward thumb buttons provide extra convenience. (Button functionality can also be changed or reassigned using third-party software.) Works on most non-metallic surfaces. The built-in lithium battery is fully rechargeable.

The J-Tech Digital V638 ergonomic mouse is a cutting edge, “handshake” design, wireless mouse with removable palm rest, thumb buttons and rechargeable battery. The ambidextrous design of the J-Tech Digital V638 greatly reduces arm/wrist/hand strain even during extended use, optimized for either hand.

Its 800 – 3200 adjustable DPI sensor not only provides precision, fluid movements on nearly any surface with the highest accuracy, but its dual sensors allow it to track movement at 90 different speeds. What’s more, J-Tech Digital’s customizable software provides the option to change button functionality or reassign buttons from layout A or B. This allows end users to configure the mouse however they want instead of using predefined layouts by the manufacturer.

10. Wireless Ergonomic BKLNOG Vertical Mouse


  • onnectivity Technology : Wireless
  • Brand : BKLNOG
  • Model Name : BE701
  • Movement Detection Technology : Optical
  • Color : Black

BKLNOG vertical mouse is one of the best ergonomic mice designed for either right-handed and left-handed users. The advanced vertical design prevents wrist extension and ulnar deviation, reducing strain on muscles and tendons. It is crafted with an ergonomically sculpted shape to keep your hand in the least strained handshake position, relieves forearm stress and carpal tunnel syndrome.

Updated for all-day comfort, the BKLNOG’s new-gen vertical mouse comes with an ergonomically sculpted shape that keeps your hand in the least stressed handshake position, significantly reduces the wrist and forearm strains caused by using a conventional mouse. One-of-a kind spots are provided on both sides of the mouse pad for every finger, providing a secure grip to reduce painful wrist tension. When you use it, you will feel like it’s not even there because it’s so lightweight and comfortable.

BKLNOG ergonomic vertical mouse is created for those who suffer from Repetitive Strain Injury (RSI) and want to protect themselves from symptoms associated with RSI such as pain in the wrist and forearm, numbness in the hands and arms. The curved design of the ergonomic vertical mouse provides a natural handshake position, significantly reducing pressure on the hand, wrist and forearm.

Leave a Comment